香蕉视频

Education

Research Interests

• Stroke
• Ion channel
• CNS Drug Development

Publications

• Huawei Sun, Tao Yang, Roger Simon, Zhi-gang Xiong, Tiandong Leng#. The role of cholesterol metabolic enzyme CYP46A1 and its metabolite 24S-hydroxycholesterol in ischemic stroke. Stroke 2024 Sep 3. doi: 10.1161/STROKEAHA.124.047803 (#corresponding author)
• Huawei Sun, Tao Yang, Roger Simon, Zhi-gang Xiong, Tiandong Leng#. Cholestane-3尾, 5伪, 6尾-triol inhibits ASICs and protects against acidosis-mediated ischemic brain injury. Stroke 2024 Apr 25. doi: 10.1161/STROKEAHA.124.046963 (#corresponding author).
• Baoming Wu, Jaree Bargaineer, Ling Zhang, Tao Yang, Zhigang Xiong and Tiandong Leng#. Upregulation of acid sensing ion channel 1a (ASIC1a) by hydrogen peroxide through JNK pathway, Acta Pharmacol 2021 Aug;42(8):1248-1255. (#corresponding author)
• Yan M, Liu AL, Zhou SJ, Tang LP, Ou YQ, Yin W, Chen XY, Su XW, Qiu PX, Huang YJ, Zhang JX, Yan GM, Leng TD#. Characterization of a synthetic 24-keto-cholest-5-en-3 , 19-Diol as a neuroprotectant. CNS Neuroscience&Therapeutics. 2015 Jun;21(6):486-95 (#corresponding author)
• Hu HY*, Zhou YH*, Leng TD*, Liu AL, Wang YQ, Yin W, Huang YJ, Zhang JX, Qiu PX, Wang LW, Sang HF and Yan The major cholesterol metabolite cholestane-3 , Sa, 6 -triol functions as an endogenous neuroprotectant. J Neurosci. 2014 Aug 20;34(34):11426-38 (*equal contribution)

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